kangar00: Kernel Approaches for Nonlinear Genetic Association Regression
Methods to extract information on pathways, genes and various single-nucleotid polymorphisms (SNPs) from online databases. It provides functions for data preparation and evaluation of genetic influence on a binary outcome using the logistic kernel machine test (LKMT). Three different kernel functions are offered to analyze genotype information in this variance component test: A linear kernel, a size-adjusted kernel and a network-based kernel (Friedrichs et al., 2017, <doi:10.1155/2017/6742763>).
| Version: | 
1.4 | 
| Depends: | 
R (≥ 3.1.0) | 
| Imports: | 
methods, bigmemory, sqldf, biomaRt, KEGGgraph, CompQuadForm, data.table, lattice, igraph | 
| Suggests: | 
testthat | 
| Published: | 
2020-02-17 | 
| Author: | 
Juliane Manitz [aut], Stefanie Friedrichs [aut], Patricia Burger [aut],
    Benjamin Hofner [aut], Ngoc Thuy Ha [aut], Saskia Freytag [ctb],
    Heike Bickeboeller [ctb] | 
| Maintainer: | 
Juliane Manitz  <r at manitz.org> | 
| License: | 
GPL-2 | 
| NeedsCompilation: | 
no | 
| Citation: | 
kangar00 citation info  | 
| CRAN checks: | 
kangar00 results | 
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