titeIR: Isotonic Designs for Phase 1 Trials with Late-Onset Toxicities

Functions to design phase 1 trials using an isotonic regression based design incorporating time-to-event information. Simulation and design functions are available, which incorporate information about followup and DLTs, and apply isotonic regression to devise estimates of DLT probability.

Version:	0.1.0
Imports:	Iso
Published:	2018-09-28
Author:	Lee McDaniel [aut, cre]
Maintainer:	Lee McDaniel <lmcda4 at lsuhsc.edu>
License:	GPL-3
NeedsCompilation:	no
CRAN checks:	titeIR results

Documentation:

Reference manual:

titeIR.pdf

Downloads:

Package source:	titeIR_0.1.0.tar.gz
Windows binaries:	r-devel: titeIR_0.1.0.zip, r-release: titeIR_0.1.0.zip, r-oldrel: titeIR_0.1.0.zip
macOS binaries:	r-release (arm64): titeIR_0.1.0.tgz, r-oldrel (arm64): titeIR_0.1.0.tgz, r-release (x86_64): titeIR_0.1.0.tgz, r-oldrel (x86_64): titeIR_0.1.0.tgz

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