replicateBE: Average Bioequivalence with Expanding Limits (ABEL)

Performs comparative bioavailability calculations for Average Bioequivalence with Expanding Limits (ABEL). Implemented are 'Method A' and 'Method B' and the detection of outliers. If the design allows, assessment of the empiric Type I Error and iteratively adjusting alpha to control the consumer risk. Average Bioequivalence - optionally with a tighter (narrow therapeutic index drugs) or wider acceptance range (Gulf Cooperation Council, South Africa: Cmax) - is implemented as well.

Version:	1.1.1
Depends:	R (≥ 3.5.0)
Imports:	readxl (≥ 1.0.0), PowerTOST (≥ 1.5.3), lmerTest, nlme, pbkrtest, graphics, grDevices
Suggests:	knitr, rmarkdown, testthat, devtools
Published:	2022-02-12
Author:	Helmut Schütz [aut, cre], Michael Tomashevskiy [ctb], Detlew Labes [ctb]
Maintainer:	Helmut Schütz <helmut.schuetz at bebac.at>
BugReports:	https://github.com/Helmut01/replicateBE/issues
License:	GPL (≥ 3)
URL:	https://github.com/Helmut01/replicateBE
NeedsCompilation:	no
Materials:	README NEWS
In views:	ClinicalTrials
CRAN checks:	replicateBE results

Documentation:

Reference manual:	replicateBE.pdf
Vignettes:	replicateBE

Downloads:

Package source:	replicateBE_1.1.1.tar.gz
Windows binaries:	r-devel: replicateBE_1.1.1.zip, r-release: replicateBE_1.1.1.zip, r-oldrel: replicateBE_1.1.1.zip
macOS binaries:	r-release (arm64): replicateBE_1.1.1.tgz, r-oldrel (arm64): replicateBE_1.1.1.tgz, r-release (x86_64): replicateBE_1.1.1.tgz, r-oldrel (x86_64): replicateBE_1.1.1.tgz
Old sources:	replicateBE archive

Linking:

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